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The expression and significance of fatty acid metabolism enzymes in the prefrontal cortex in autistic brain

作者:陈建玲theexpressionsignificancefattyacidmetabolismenzymes

摘要:Objective To investigate the expression difference offatty acid synthase (FAS),acetyl coenzyme A synthetase1 ( AceCS1 ),long-chain acyl -coenzyme A synthetase1 (ACSL1) and acetyl-CoA carboxylase (ACC) in theprefrontal cortex in the brain specimens from autistic subjectsand control subjects. Methods Eight autistic brainspecimens and eight control brain specimens were used.The autistic brain specimens were bought from Brain andTissue Bank for Developmental Disorders ( BTBDD),whereas the control brain specimens were bought fromNational Institute of Child Health and Human Development(NICHD). The expression of FAS,AceCS1,ACSL1and ACC in prefrontal cortex of the brain specimenswere detected using western blotting method.

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中国医学文摘·耳鼻咽喉科学

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