作者：李歌profileserummetabonomicsstudygastriccancer
摘要：Objective To detect whether patients with gastriccancer have unique serum metabolomic characteristics byliquid chromatography-mass spectrometry ( LC-MS )metabolomic analysis,and to screen potential markers forearly gastric cancer and to preliminarily explore the relatedmetabolic pathways. Methods At the First AffiliatedHospital of Soochow University,66 patients with gastriccancer and 44 patients with benign gastric disease fromJuly,2017 to January,2018 were enrolled,and 50healthy subjects served as controls. Twenty-five patientswith gastric cancer at stage Ⅰ and Ⅱ and 25 patientswith gastric cancer at stage Ⅲ and Ⅳ were selected fromthe 66 patients with gastric cancer,and 25 subjects werealso selected from 50 healthy controls. The plasma smallmolecule metabolites of patients with gastric cancer andbenign gastric disease and healthy controls were detectedby LC-MS method.
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