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Active vitamin D prevents podocyte injury via regulation of macrophage M1 and M2 phenotype in diabetic nephropathy rats

作者:郭银凤phenotypemacrophagevitaminimpairmentnephrinprotectingvitaminurineinhibitingregulate

摘要:Objective To investigate the effect of active vitamin D(VD)on macrophage M1 and M2 phenotype and its role in protecting podocyte impairment in diabetic nephropathy(DN).Methods Diabetes mellitus rats were established by intraperitoneal injection with streptozocin.Rats were randomly divided into four groups:normal-1(NC-1,n=8),normal-2(NC-2,n=8,normal rats treated with calcitriol 0.1μg·kg-1·d-1by gavages),

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中国医学文摘·耳鼻咽喉科学

《中国医学文摘·耳鼻咽喉科学》是一本有较高学术价值的双月刊,自创刊以来,选题新奇而不失报道广度,服务大众而不失理论高度,颇受业界和广大读者的关注和好评。

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