The effect of NALP3 inflammasome pathway in visceral adipose tissue on the development of insulin resistance in catch-up growth after food restriction in rats

作者：李燕visceraladiposecatchclampinfusioncaspaseleucinecleavagepressioncreased

摘要：Objective To investigate the effects of catch-up growth(CUG)on the natch domain,leucine-rich repeat and PVD-containing protein 3(NALP3)inflammasome pathway in visceral adipose tissue(VAT)and the mechanism of insulin resistance(IR)in CUG.Methods Sprague-Dawley rats were randomly divided into the normal chow(NC)and the catch-up growth group(CUG).General characteristics,glucose infusion rate60-120(GIR60-120)in hyperinsulinemic-euglycemic clamp and expression of NALP3 inflammasome,caspase1(p10)and

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