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Novel anti-AD dimeric leads:from relieving symptoms to modifying diseases via multi-targets

作者:HAN; Yi-fan; HU; Sheng-quan; Marvin; M...alzheimerdiseasedimericleadsrelievingsymptomsmodifyingdiseases

摘要:Alzheimer disease(AD) has now become the most common brain disorder among the older population. In addition, the currently existing therapeutics only offer temporary symptomatic relieves. Therefore, further research and development of more efficacious and disease-modifying agents for the prevention, treatment and restoration of AD will have tremendous value from both scientific, and economic standpoints. Over the past few years, our series of studies have identified several highly promising anti-AD dimeric leads, with disease-modifying potentials. In this presentation, the latest progress on the neuroprotective and disease modifying effects and the underlying mechanisms of those candidates will be comprehensively illustrated and discussed.

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中国药理学与毒理学

《中国药理学与毒理学杂志》(CN:11-1155/R)是一本有较高学术价值的大型月刊,自创刊以来,选题新奇而不失报道广度,服务大众而不失理论高度。颇受业界和广大读者的关注和好评。 《中国药理学与毒理学杂志》为专业学术性刊物。主要刊登实验药理学与实验毒理学方面的研究论著、简报、短讯、专题述评和短篇综述。

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