作者：梁鹏 杜凡 赵美燕 梁万琴 Mei-yan Wan-qi...螺旋平扫动态增强扫描肺孤立性结节病变鉴别诊断价值solitarypulmonarynodulesdiagnosisofspiralct恶性结节lungcarcinoma良性结节周围型肺癌结核球contrastdynamic形态significantpathology密度曲线
摘要：目的 探讨螺旋CT动态增强扫描对肺孤立性结节病变的良、恶性鉴别诊断价值.方法 经病理证实的62例肺孤立性结节,平扫后,以2 ml/s速率注入造影剂后1、2、3、4、5 min薄层扫描.分析强化值、时间-密度曲线及强化形态对良、恶性结节的鉴别价值.结果 恶性结节的强化值(49±15)Hu明显高于良性结节(18±16)Hu(P＜0.01).周围型肺癌的主要强化形态是完全性强化及周围性强化.恶性结节增强后CT值立即升高,2 min形成强化高峰,然后逐渐下降,而良性结节特别是结核球增强后CT值缓慢上升,无明显峰值出现.结核球的主要强化形态是无强化及包膜样强化,占92.3%.结论 强化值≤15 Hu提示良性结节;强化值＞20 Hu考虑恶性结节.动态增强CT对周围型肺癌与结核球的鉴别有较高价值. Abstract： Objective To analyze the feature of the solitary pulmonary nodules at dynamic contrast-enhanced spiral CT. Methods Sixty-two patients with solitary pulmonary nodules proved by pathology were studied. Thin-section CT scans were obtained before and after enhancement 1,2,3,4 and 5 minutes. Results Malignant nodules enhanced (49±15)Hu significantly more than benign nodules (18±16)Hu. The major enhancement pattern of peripheral lung carcinoma was complete enhancement, a little show peripheral enhancement. Tuberculoma show capsular enhancement or non enhancement. Conclusions Absence of significant lung noldue enhancement (≤15 Hu) at CT is strongly predictive of benignity.Malignant nodules enhanced significantly more than benign nodules. Dynamic contrast enhanced CT is useful in the differential diagnosis of lung carcinoma and tuberculoma.
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