作者：吴道仙 邓春晓 Dao-xian Chun-xiao封管液白血病患者外周导入中心静脉置管留置效果centralsodiumchloride对照组统计学意义difference生理盐水control肝素钠盐水发生率穿刺点two置管化疗细胞外液出血率比较差异results
摘要：目的 比较两种封管液对白血病患者外周导入中心静脉置管(PICC)留置效果的影响.方法 将60例应用PICC置管化疗的白血病患者随机分为观察组和对照组各30例.观察组用0.9%生理盐水作封管液,对照组用肝素钠盐水(含肝素钠50 U/L)作封管液.结果 观察组与对照组PICC穿刺点出血率比较差异有统计学意义(P＜0.05),而观察组与对照组静脉炎发生率、PICC管的堵管率比较,差异无统计学意义(P均＞0.05).结论 生理盐水能维持细胞外液容量及渗透压,符合生理要求,可代替肝素盐水封管,以减少PICC穿刺点出血的发生率. Abstract： Objective To explore the effects of the two injection liquids to seal trochars in patients with ieukemia by peripherally inserted central catheter. Methods Sixty cases of ieukemia were randomly divided into the observation group (30 cases) and the control group (30 cases). For the observation group, 0.9% sodium chloride injection was adopted to seal the trochars, while for the control group, sodium chloride injection containing heparin sodium (heparin sodium 50 U/ml) was adopted. The sealing effects of these two kinds of injections were compared. Results There was statistical difference between the two groups in the rate of the puncture ( P ＜ 0.05 ). While there was no statistical difference between the two groups in the rate of phlebitis or the rate of blockage ( P ＞ 0.05 ). Conclusions 0.9% sodium chloride injection may presrve extracellular fluid volume and osmotic pressure. Therefore, 0.9% sodium chloride injection can replace sodium chloride injection containing heparin sodium ( heparin sodium 50 U/ml) in order to seal venous trochars for neonates and to minimize the hemorrhaging at the puncture.
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