作者：李强; 陈钧辉; 张冬梅; 包燕雏; 张海燕; ...人尿抗菌物质三甲氧苄二氨基嘧啶分离纯化鉴定二氢叶酸还原酶抑制剂化学药物细菌感染
摘要：In order to explain the special antibiotic activity of urine, various chromatographic techniques were applied to separate and purify the key component from the healthy male urine. The structure of purified component was identified by mass spectrometry and NMR. The results indicated that the substance separated from the male urine was trimethoprim. This is the first report of trimethoprim separated from urine.
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