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The effect of inhibitor peptide for ADAM8 in attenuating ovalbumin-induced murine asthma

作者:Jun Chen Xuemei Jiang Yiyuan Duan Jiao...asthmaovalbuminadamairwaytargetingtargetedundesirablemodulatingrequiringmurine

摘要:Targeted peptides have been identified as showing great promise for treatment of various diseases including asthma.Asthma is considered of difficuIt-to-treat due to its unclear etiology,thus usually requiring life-long treatment.Current strategies for asthma therapy are hampered with undesirable side effects,poor targeting and failure in modulating airway hyperresponsiveness,leading to pressing need of developing more targeted and effective therapeutic sites for asthma.Recently,a disintegrin and metalloproteinase 8(ADAM8)have been shown to over-

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医用生物力学

《医用生物力学》(CN:31-1624/R)是一本有较高学术价值的大型双月刊,自创刊以来,选题新奇而不失报道广度,服务大众而不失理论高度。颇受业界和广大读者的关注和好评。 《医用生物力学》主要刊登交流我国学者在生物力学研究中取得的成果和部分国外专家的论文。着重刊登对科研与临床实践有指导意义的论著,同时还开辟综述、讲座、经验交流、研究简报、专题讨论等专栏。内容充实,反映了中国生物力学的研究动向和成果。

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