作者:Xiao-Mei; Yu; Michael; Byrne; Ashley; ...deficientcollagenhomeostasisphenotypegenotypeclusteredclonestomachtargeting
摘要:<正>Collagen homeostasis is critical to lung and bone stability and collagen degradation may play a role in lung and bone development,growth,and disease.Mice have two major collagenases,collagenase-2(MMP8)and collagenase-3(MMP13).To determine the roles of these collagenases we generated mice deficient in both MMP8 and MMP13.Although we had previously generated mice
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